Description

2-Aminophenylboronic Acid Pinacol Ester is a protected boronic acid derivative that serves as a crucial synthetic intermediate in modern organic chemistry. Its value lies in the dual functionality of the aromatic amine and the protected boronate ester, enabling precise cross-coupling and functional group transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing advanced small molecules and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Organic Electronics & OLED Materials: Serves as a precursor for constructing complex conjugated molecular architectures used in light-emitting diodes and organic semiconductors.
• Polymer & Resin Modification: Enables the incorporation of functional aromatic amines into polymer backbones for specialty resins and advanced materials.
• Chemical Biology & Probe Development: Utilized in synthesizing molecular probes and bioconjugation reagents for diagnostic and research applications.
• Catalyst & Ligand Synthesis: Acts as a precursor for creating novel ligands and organometallic catalysts used in asymmetric synthesis.

Basic Information

Product Name	2-Aminophenylboronic Acid Pinacol Ester
CAS No.	191171-55-8
Molecular Formula	C12H18BNO2
Molecular Weight	219.09 g/mol
Synonyms	2-Aminobenzeneboronic Acid Pinacol Ester; (2-Aminophenyl)boronic Acid Pinacol Ester; 2-Aminophenylboronic Acid Pinanediol Ester (common alternative); 2-NH2-PhBpin; B-(2-Aminophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-Aminophenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-Amino Benzeneboronic Acid Pinacol Cyclic Ester; 2-APBA Pinacol Ester
EINECS	Contact for details

Quality Control

Our 2-Aminophenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.