Description

Telithromycin CAS NO 191114-48-4 is a semi-synthetic ketolide antibiotic derived from erythromycin, specifically designed to combat respiratory tract infections caused by resistant bacterial strains. Its primary value lies in its potent activity against macrolide-resistant *Streptococcus pneumoniae* and atypical pathogens, making it a critical agent in the antimicrobial arsenal. This compound is essential for pharmaceutical manufacturers and research institutions focused on developing and producing advanced antibacterial therapies, particularly for community-acquired pneumonia, acute bacterial sinusitis, and chronic bronchitis.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of finished dosage forms, specifically oral tablets, for the treatment of respiratory infections.
• Antibacterial Research & Development: Serves as a key reference standard and intermediate in R&D for novel ketolide antibiotics and studying bacterial resistance mechanisms.
• Veterinary Medicine: Potential application in developing treatments for bacterial infections in animals, subject to regional regulatory approvals.
• Microbiological Studies: Used in laboratory settings for in-vitro susceptibility testing and pharmacological studies against Gram-positive and atypical bacteria.

Basic Information

Product Name	Telithromycin
CAS No.	191114-48-4
Molecular Formula	C43H65N5O10
Molecular Weight	812.00 g/mol
Synonyms	Ketek; HMR 3647; RU-66647; Telithromycinum; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-{[(2R,3R,4S,6R)-3-hydroxy-6-methyl-4-(methylamino)oxan-2-yl]oxy}-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
EINECS	Contact for details

Quality Control

Our Telithromycin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR spectroscopy, and stringent control of related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with cGMP and relevant pharmacopeial standards for pharmaceutical intermediates and APIs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm
Microbial Limits	Conforms to EP/USP

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.