Description

2-Pyrrolidinecarboxaldehyde,5-Oxo-1-(2,4-Pentadienyl)-,[S-(E)]-(9Ci) is a chiral, non-proteinogenic amino acid derivative featuring a pyrrolidone core and a conjugated pentadienyl side chain. This compound is a high-value synthetic intermediate prized for its unique stereochemistry and functional group array, enabling the construction of complex molecular architectures. It is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for applications in medicinal chemistry and advanced material science.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in neurological and metabolic disorder research.
• Asymmetric Catalysis Ligand Precursor: Used in the development of novel chiral ligands and organocatalysts for stereoselective synthesis.
• Peptidomimetic & Proline Analogue Synthesis: Serves as a constrained scaffold for designing peptide mimics and modified amino acids with enhanced biological stability.
• Chemical Biology Probe Development: Employed in the creation of molecular probes and tool compounds for studying enzyme mechanisms and protein interactions.
• Advanced Material Synthesis: A monomer or functionalizing agent for specialty polymers and smart materials requiring specific chiral centers.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development in organic synthesis and total synthesis projects.

Basic Information

Item	Details
Product Name	2-Pyrrolidinecarboxaldehyde,5-Oxo-1-(2,4-Pentadienyl)-,[S-(E)]-(9Ci)
CAS No.	191098-87-0
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	(S,E)-1-(Penta-2,4-dien-1-yl)-5-oxopyrrolidine-2-carbaldehyde; 1-(2,4-Pentadienyl)-5-oxo-(S)-2-pyrrolidinecarboxaldehyde; 5-Oxo-1-(2,4-pentadienyl)-L-prolinal; (S)-1-(2,4-Pentadienyl)-5-oxopyrrolidine-2-carboxaldehyde; L-Prolinal, 1-(2,4-pentadienyl)-5-oxo-; Chiral pyrrolidone aldehyde; (S,E)-configured pyrrolidinecarboxaldehyde derivative
EINECS	Contact for details

Quality Control

Every batch of our 2-Pyrrolidinecarboxaldehyde,5-Oxo-1-(2,4-Pentadienyl)-,[S-(E)]-(9Ci) is produced under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and enantiomeric excess meet your research or production specifications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic results (HPLC, GC, NMR, IR, [α]D) are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store the product under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C. The material is easily oxidized and light-sensitive; allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake and thermal stress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Specific Rotation ([α]D20)	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.