Description

Quinoline-8-Boronic Acid, Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing quinoline-based scaffolds in drug discovery and development programs.
• Agrochemical Research: Used in the synthesis of novel active ingredients and fungicides requiring specific heterocyclic architectures.
• Materials Science & OLED Development: Serves as a precursor for creating organic electronic materials, including ligands for metal complexes and emissive layers.
• Academic & Industrial R&D: Fundamental building block for methodological studies in cross-coupling catalysis and new reaction development.
• Ligand Synthesis for Catalysis: Used to prepare sophisticated nitrogen-boron containing ligands for asymmetric catalysis.
• Chemical Library Production: Enables the rapid, parallel synthesis of diverse compound libraries for high-throughput screening.

Basic Information

Product Name	Quinoline-8-Boronic Acid, Pinacol Ester
CAS No.	190788-62-6
Molecular Formula	C₁₅H₂₀BNO₂
Molecular Weight	257.14 g/mol
Synonyms	8-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline; Quinolin-8-ylboronic Acid Pinacol Ester; 8-Quinolineboronic Acid Pinacol Ester; 8-(Pinacolatoboryl)quinoline; 8-Quinolylboronic Acid Pinacol Ester; B-(8-Quinolinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our Quinoline-8-Boronic Acid, Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality management system is designed to meet the rigorous standards required for research and development use in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal quality and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.