Description

2-Methoxyphenylboronic Acid Pinacol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in its enhanced stability compared to the free boronic acid, facilitating handling and storage while remaining highly reactive in key cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for the palladium-catalyzed formation of carbon-carbon bonds, widely used in pharmaceutical and material science R&D.
• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl or substituted phenyl motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Organic Electronic Materials: A building block for creating conjugated polymers and small molecules used in OLEDs, organic photovoltaics, and sensors.
• Chemical Biology Probes: Useful for modifying biomolecules or creating activity-based probes for studying biological processes.

Basic Information

Product Name	2-Methoxyphenylboronic Acid Pinacol Ester
CAS No.	190788-60-4
Molecular Formula	C13H19BO3
Molecular Weight	234.10 g/mol
Synonyms	2-Methoxyphenylboronic Acid Pinanediol Ester; (2-Methoxyphenyl)boronic Acid Pinacol Ester; 2-Methoxybenzeneboronic Acid Pinacol Ester; 2-Methoxybenzeneboronic Acid 1,3,2-Dioxaborinane Ester; 2-Methoxyphenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-Methoxy Phenyl Boronic Acid Pinacol Ester; B-(2-Methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-Methoxyphenylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis and maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.