Description

2-Nitrobenzeneboronic Acid Pinacol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its enhanced stability compared to the free boronic acid, making it an ideal reagent for Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for constructing complex aromatic and heteroaromatic systems.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides by introducing functionalized phenyl groups into target molecules.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and conductive polymers, where precise molecular architecture is required.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for fine chemical producers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	2-Nitrobenzeneboronic Acid Pinacol Ester
CAS No.	190788-59-1
Molecular Formula	C₁₂H₁₆BNO₄
Molecular Weight	249.07 g/mol
Synonyms	2-Nitrophenylboronic Acid Pinacol Ester; (2-Nitrophenyl)boronic Acid Pinacol Ester; 4,4,5,5-Tetramethyl-2-(2-nitrophenyl)-1,3,2-dioxaborolane; Pinacol 2-Nitrobenzeneboronate; 2-Nitrobenzeneboronic Acid, Pinacol Ester; 2-Nitrophenylboronic Acid, Pinacol Ester; B-(2-Nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-Nitrobenzeneboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.