Description

3-[(Trimethylsilyl)Ethynyl]Benzonitrile is a versatile organosilicon building block featuring both a nitrile and a protected acetylene functional group. This compound is valued for its role as a key intermediate in advanced organic synthesis, particularly in cross-coupling reactions and the construction of complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A crucial synthon for the synthesis of complex drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides with tailored biological activity.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in the preparation of sophisticated ligands for transition metal catalysis.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and chemical biology research.
• Fine Chemical Production: Integral to the multi-step synthesis of high-value, low-volume specialty chemicals.

Basic Information

Product Name	3-[(Trimethylsilyl)Ethynyl]Benzonitrile
CAS No.	190771-22-3
Molecular Formula	C12H13NSi
Molecular Weight	199.33 g/mol
Synonyms	3-[(Trimethylsilyl)ethynyl]benzonitrile; 3-(Trimethylsilylethynyl)benzonitrile; m-[(Trimethylsilyl)ethynyl]benzonitrile; 3-Cyano-phenyl(trimethylsilyl)acetylene; Benzonitrile, 3-[(trimethylsilyl)ethynyl]-; TMS-Ethynylbenzonitrile; 3-(TMS-ethynyl)benzonitrile; 3-(Trimethylsilylethynyl)phenyl cyanide
EINECS	Contact for details

Quality Control

Our 3-[(Trimethylsilyl)Ethynyl]Benzonitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.