Description

2-Aziridinecarboxylicacid,2-(Aminocarbonyl)-1-Fluoro-,Methylester(9Ci) CAS NO 190184-62-4 is a specialized fluorinated aziridine derivative, a high-value building block prized for its unique reactive aziridine ring and fluorine substituent. This compound matters for its role in advanced organic synthesis, enabling the construction of complex molecules with precise stereochemistry and enhanced biological activity. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in oncology and antiviral research, where the aziridine moiety can act as an alkylating agent.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its fluorine atom to improve metabolic stability and membrane permeability.
• Peptidomimetic Chemistry: Serves as a constrained amino acid analog for designing peptide-like molecules with modified backbone structures to enhance proteolytic stability.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with specific functional groups and tailored properties.
• Chemical Biology Probes: Utilized in the synthesis of activity-based probes (ABPs) to study enzyme function and mechanism in biological systems.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Item	Details
Product Name	2-Aziridinecarboxylicacid,2-(Aminocarbonyl)-1-Fluoro-,Methylester(9Ci)
CAS No.	190184-62-4
Molecular Formula	C5H7FN2O3
Molecular Weight	162.12 g/mol
Synonyms	1-Fluoro-2-(aminocarbonyl)aziridine-2-carboxylic acid methyl ester; Methyl 1-fluoro-2-carbamoylaziridine-2-carboxylate; 2-Carbamoyl-1-fluoroaziridine-2-carboxylic acid methyl ester; Aziridine-2-carboxylic acid, 2-(aminocarbonyl)-1-fluoro-, methyl ester (9CI); 1-Fluoro-2-carbamoylaziridine-2-carboxylic acid methyl ester; 190184-62-4; Methyl 2-carbamoyl-1-fluoroaziridine-2-carboxylate
EINECS	Contact for details

Quality Control

Our 2-Aziridinecarboxylicacid,2-(Aminocarbonyl)-1-Fluoro-,Methylester(9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.