Description

2H-1-Benzopyran-2-One, 6-Bromo-3-Ethyl-4-Hydroxy- is a high-purity, functionalized coumarin derivative, serving as a critical synthetic intermediate and building block in advanced organic chemistry. Its value lies in the strategic placement of bromine and hydroxyl groups, which enable selective functionalization for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its coumarin core for bioactive molecule design.
• Organic Synthesis: Serves as a versatile precursor for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) due to the reactive bromine substituent.
• Fluorescent Probe Development: The coumarin scaffold is a classic fluorophore; this derivative can be used to create specialized fluorescent dyes and sensors for biochemical analysis.
• Material Science: Potential monomer or additive in the synthesis of specialty polymers and organic electronic materials.
• Academic & R&D: A valuable reagent for methodological studies in synthetic organic chemistry and for exploring new chemical transformations.

Basic Information

Product Name	2H-1-Benzopyran-2-One, 6-Bromo-3-Ethyl-4-Hydroxy-
CAS No.	189873-61-8
Molecular Formula	C₁₁H₉BrO₃
Molecular Weight	269.09 g/mol
Synonyms	6-Bromo-3-ethyl-4-hydroxycoumarin; 6-Bromo-3-ethyl-4-hydroxy-2H-chromen-2-one; 3-Ethyl-6-bromo-4-hydroxycoumarin; 4-Hydroxy-6-bromo-3-ethylcoumarin; 6-Bromo-4-hydroxy-3-ethyl-2H-chromen-2-one; 189873-61-8; 6-Bromo-3-ethyl-4-hydroxy-2H-1-benzopyran-2-one
EINECS	Contact for details

Quality Control

Our 2H-1-Benzopyran-2-One, 6-Bromo-3-Ethyl-4-Hydroxy- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.