Description

4,4-Difluoro-1-(4-Methoxy-Phenyl)-Butane-1,3-Dione is a high-purity fluorinated diketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile precursor in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, heterocyclic compounds, and materials science applications.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, including potential kinase inhibitors and anti-inflammatory agents.
• Agrochemical Research: Used in developing novel fluorinated pesticides and herbicides, where the fluorine atoms can enhance biological activity and stability.
• Ligand & Catalyst Development: Serves as a precursor for β-diketonate ligands used in coordination chemistry and catalysis.
• Material Science: Employed in the synthesis of fluorinated organic compounds for advanced polymers and electronic materials.
• Chemical Synthesis Building Block: Utilized in cyclization reactions, such as the formation of pyrazoles and other heterocyclic cores.
• Academic & Industrial R&D: Essential for exploratory chemistry in universities and corporate research laboratories focusing on fluorine chemistry.

Basic Information

Product Name	4,4-Difluoro-1-(4-Methoxy-Phenyl)-Butane-1,3-Dione
CAS No.	189347-40-8
Molecular Formula	C11H10F2O3
Molecular Weight	228.19 g/mol
Synonyms	1-(4-Methoxyphenyl)-4,4-difluorobutane-1,3-dione; 4,4-Difluoro-1-(4-methoxyphenyl)-1,3-butanedione; 4'-Methoxy-4,4-difluoro-1-phenyl-1,3-butanedione; 4,4-Difluoro-1-(4-methoxyphenyl)butane-1,3-dione; DFMPBD
EINECS	Contact for details

Quality Control

Our 4,4-Difluoro-1-(4-Methoxy-Phenyl)-Butane-1,3-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.