Description

(R)-1-(4-Benzyloxy-3-Nitrophenyl)-2-Bromoethanol is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry and functional groups make it a critical precursor for constructing complex, optically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly where stereochemical purity is essential for biological activity.
• Asymmetric Synthesis: Used as a starting material or intermediate in catalytic asymmetric reactions to introduce chirality into target molecules.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and agrochemicals.
• Academic and Industrial R&D: A valuable tool for methodological studies in organic chemistry and process development in pilot-scale operations.

Basic Information

Product Name	(R)-1-(4-Benzyloxy-3-Nitrophenyl)-2-Bromoethanol
CAS No.	188690-82-6
Molecular Formula	C15H14BrNO4
Molecular Weight	352.18 g/mol
Synonyms	(R)-2-Bromo-1-(4-(benzyloxy)-3-nitrophenyl)ethanol; (R)-1-(4-Benzyloxy-3-nitrophenyl)-2-bromoethan-1-ol; (R)-α-Bromo-4-(benzyloxy)-3-nitrobenzenemethanol; 188690-82-6; (R)-enantiomer of 1-(4-Benzyloxy-3-nitrophenyl)-2-bromoethanol; BRN 8518755
EINECS	Contact for details

Quality Control

Our (R)-1-(4-Benzyloxy-3-Nitrophenyl)-2-Bromoethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.