Description

3-Aminocarbonylphenylboronic Acid, Pinacol Ester is a protected boronic acid derivative, a crucial intermediate in modern synthetic chemistry. Its primary value lies in its enhanced stability compared to the free boronic acid, making it an essential building block for Suzuki-Miyaura cross-coupling reactions. This compound is particularly sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science: Employed in the creation of organic electronic materials, such as polymers for OLEDs and organic photovoltaics, where precise molecular architecture is critical.
• Chemical Biology & Proteomics: Serves as a versatile handle for bioconjugation and the development of molecular probes and inhibitors.
• Academic & Industrial R&D: A fundamental reagent for methodological development in synthetic organic chemistry and catalysis research.
• Ligand Synthesis: Used as a precursor for creating sophisticated ligands in coordination chemistry and catalysis.

Basic Information

Product Name	3-Aminocarbonylphenylboronic Acid, Pinacol Ester
CAS No.	188665-74-9
Molecular Formula	C13H18BNO3
Molecular Weight	247.10 g/mol
Synonyms	3-Carbamoylphenylboronic Acid Pinacol Ester; (3-Carbamoylphenyl)boronic Acid Pinacol Ester; 3-Aminocarbonylbenzeneboronic Acid Pinacol Ester; 3-Borono-N-(tert-butyl)benzamide Pinacol Ester (related); 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; Pinacol 3-Carbamoylphenylboronate; B-(3-Aminocarbonylphenyl)boronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our 3-Aminocarbonylphenylboronic Acid, Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive applications like pharmaceutical synthesis. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and LC-MS. Our quality system is designed to meet the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.