Description

5-Acetyltaxachitriene A is a specialized taxane derivative, a class of compounds renowned for their complex diterpenoid structure and significant biological activity. This high-purity intermediate is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology drug discovery and the development of next-generation taxane-based pharmaceuticals.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of novel taxane-based chemotherapeutic agents.
• Oncology Research: Used in biochemical and pharmacological studies to investigate structure-activity relationships (SAR) and mechanisms of action against cancer cell lines.
• Reference Standard: Employed as a high-purity analytical standard in quality control (QC) and method development for HPLC and LC-MS analysis of taxane compounds.
• Semi-Synthesis: Acts as a starting material or intermediate for the semi-synthetic modification of taxane scaffolds to enhance potency, reduce toxicity, or improve pharmacokinetic properties.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic chemistry, natural product synthesis, and medicinal chemistry.

Basic Information

Product Name	5-Acetyltaxachitriene A
CAS No.	187988-48-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	5-Acetyltaxachitriene A; (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-Diacetoxy-1,9-dihydroxy-15-[(2R,3S)-3-[(2S,3R,4S,5R)-5-ethyl-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl]oxy-2-hydroxy-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl benzoate; Taxachitriene A, 5-acetyl-; Related taxane derivative intermediates.
EINECS	Contact for details

Quality Control

Our 5-Acetyltaxachitriene A is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by advanced chromatographic methods. We are committed to meeting the stringent requirements of pharmaceutical R&D and can provide support for regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.