Description

3,5-Bis[[(1,1-Dimethylethyl)dimethylsilyl]oxy]benzaldehyde is a high-purity, protected benzaldehyde derivative featuring two tert-butyldimethylsilyl (TBDMS) ether groups. This compound matters as a critical, versatile synthetic intermediate, offering chemoselective protection for phenolic hydroxyl groups and enabling complex multi-step organic synthesis under mild conditions. It is primarily needed by pharmaceutical R&D teams, agrochemical manufacturers, and advanced material scientists for constructing complex molecular architectures, including natural products and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly those requiring selective protection/deprotection strategies.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where the protected aldehyde functionality is essential.
• Organic Synthesis Reagent: Serves as a versatile precursor for creating ligands, catalysts, and other fine chemicals in academic and industrial laboratories.
• Material Science Research: Employed in the development of specialty polymers, dendrimers, and functional organic materials.
• Natural Product Synthesis: Facilitates the total synthesis of complex natural compounds with sensitive functional groups.
• Chemical Biology Probes: Acts as a starting material for creating molecular probes and tags used in biochemical research.

Basic Information

Product Name	3,5-Bis[[(1,1-Dimethylethyl)dimethylsilyl]oxy]benzaldehyde
CAS No.	187803-40-3
Molecular Formula	C21H38O3Si2
Molecular Weight	406.70 g/mol
Synonyms	3,5-Bis[(tert-butyldimethylsilyl)oxy]benzaldehyde; 3,5-Bis-O-(tert-butyldimethylsilyl)benzaldehyde; 3,5-Di-O-TBDMS-benzaldehyde; Benzaldehyde, 3,5-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-; 3,5-Bis(tert-butyldimethylsiloxy)benzaldehyde; 3,5-Bis(TBDMSO)benzaldehyde; 3,5-Di-(tert-butyldimethylsilyloxy)benzaldehyde
EINECS	Contact for details

Quality Control

Our 3,5-Bis[[(1,1-Dimethylethyl)dimethylsilyl]oxy]benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures material consistency and reliability for your critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep away from heat, sparks, and open flames. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.