Description

2-(2,4-Difluorophenyl)-1-(4-Fluorophenyl)Ethanone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals, where its unique difluorophenyl and fluorophenyl motifs are key to modulating biological activity and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce specific fluorine-substituted aromatic structures into novel molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in therapeutic areas requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where fluorine atoms improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Employed as a monomer or modifier to introduce fluorine-containing aromatic units into high-performance polymers.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and the exploration of new chemical entities.
• Fluorine Chemistry Studies: Used as a model compound in academic and industrial research focused on the synthesis and reactivity of polyfluorinated aromatics.

Basic Information

Product Name	2-(2,4-Difluorophenyl)-1-(4-Fluorophenyl)Ethanone
CAS No.	187617-93-2
Molecular Formula	C14H9F3O
Molecular Weight	250.22 g/mol
Synonyms	1-(4-Fluorophenyl)-2-(2,4-difluorophenyl)ethanone; 2',4'-Difluoro-4-fluorochalcone; 4-Fluoro-2',4'-difluorochalcone; (4-Fluorophenyl)(2,4-difluorophenyl)methanone (tautomeric form); 2-(2,4-Difluorophenyl)-1-(4-fluorophenyl)ethan-1-one; DFPE; 187617-93-2
EINECS	Contact for details

Quality Control

Our 2-(2,4-Difluorophenyl)-1-(4-Fluorophenyl)Ethanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.