Description

Methyl 2,5-Dibromo-4-Fluorobenzoate is a high-purity, multi-functional halogenated aromatic ester serving as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine and fluorine substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine and bromine atoms contribute to enhanced biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for creating halogenated aromatic cores used in electronic materials, contributing to improved charge transport and thermal stability.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination, enabling the rapid diversification of chemical libraries for drug discovery.
• Fluorinated Dye & Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where fluorine incorporation improves light fastness and color properties.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, particularly in halogenation chemistry and regioselective functionalization.

Basic Information

Product Name	Methyl 2,5-Dibromo-4-Fluorobenzoate
CAS No.	187326-21-2
Molecular Formula	C8H5Br2FO2
Molecular Weight	311.93 g/mol
Synonyms	2,5-Dibromo-4-fluorobenzoic acid methyl ester; Methyl 2,5-dibromo-4-fluorobenzoate; Benzoic acid, 2,5-dibromo-4-fluoro-, methyl ester; 4-Fluoro-2,5-dibromobenzoic acid methyl ester; Methyl 4-fluoro-2,5-dibromobenzoate; 2,5-Dibromo-4-fluorobenzoic acid, methyl ester; Methyl ester of 2,5-dibromo-4-fluorobenzoic acid
EINECS	Contact for details

Quality Control

Every batch of Methyl 2,5-Dibromo-4-Fluorobenzoate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Single impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.