Description

n-Pentafluorophenyldichloromaleimide is a highly functionalized, fluorinated maleimide derivative, a key building block in advanced organic synthesis. Its value lies in the unique reactivity of the dichloromaleimide core combined with the electron-withdrawing and lipophilicity-enhancing properties of the pentafluorophenyl group. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients, functional materials, and as a precursor for complex heterocyclic systems.

Application

• Pharmaceutical Intermediate: Serves as a critical synthon for the construction of complex drug candidates, especially those targeting protein-protein interactions or requiring specific pharmacokinetic profiles.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for creating high-performance polymers with enhanced thermal stability, chemical resistance, and specific surface properties.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for catalysis or as a scaffold for metal-organic frameworks (MOFs).
• Fluorinated Compound Library: A valuable starting material for medicinal chemistry and discovery chemistry to build diverse libraries of fluorinated compounds for screening.
• Peptide & Bioconjugation Chemistry: The reactive maleimide group can be utilized for selective bioconjugation with thiol groups on proteins or peptides.

Basic Information

Product Name	n-Pentafluorophenyldichloromaleimide
CAS No.	186958-58-7
Molecular Formula	C10Cl2F5NO2
Molecular Weight	340.01 g/mol
Synonyms	2,3-Dichloro-4-(pentafluorophenyl)-1H-pyrrole-2,5-dione; 2,3-Dichloromaleic Pentafluorophenylimide; 4-(Perfluorophenyl)-2,3-dichloromaleimide; Pentafluorophenyl Dichloromaleimide; 2,3-Dichloro-1H-pyrrole-2,5-dione, 4-(pentafluorophenyl)-; Dichloro(pentafluorophenyl)maleimide
EINECS	Contact for details

Quality Control

Every batch of n-Pentafluorophenyldichloromaleimide is manufactured and tested under strict quality management protocols to ensure consistency and purity for research and production use. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.