Description

3-Chloro-2-Fluoro-6-(Trifluoromethyl)Benzoyl Chloride is a highly reactive and versatile aromatic acid chloride intermediate. Its value lies in its unique trifluoromethyl and halogen substitution pattern, which is critical for imparting desirable properties like metabolic stability and lipophilicity in advanced molecules. This compound is essential for researchers and manufacturers in the agrochemical and pharmaceutical industries, particularly for the synthesis of novel active ingredients and complex organic building blocks.

Application

• Agrochemical Intermediate: A key building block for the synthesis of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), especially for molecules requiring a halogenated benzoyl moiety for targeted drug design.
• Liquid Crystal Material Synthesis: Serves as a precursor in the production of fluorinated liquid crystals used in advanced display technologies.
• Organic Synthesis Building Block: Employed in coupling reactions, such as Friedel-Crafts acylation and amide bond formation, to introduce a functionalized benzoyl group into more complex molecular architectures.
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers, including polyamides and polyesters, to incorporate halogenated aromatic units.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for exploring new synthetic pathways and creating novel fluorinated compounds.

Basic Information

Product Name	3-Chloro-2-Fluoro-6-(Trifluoromethyl)Benzoyl Chloride
CAS No.	186517-45-3
Molecular Formula	C8H2Cl2F4O
Molecular Weight	261.00 g/mol
Synonyms	3-Chloro-2-fluoro-6-(trifluoromethyl)benzoyl chloride; 2-Fluoro-3-chloro-6-(trifluoromethyl)benzoyl chloride; 6-(Trifluoromethyl)-3-chloro-2-fluorobenzoyl chloride; Benzoyl chloride, 3-chloro-2-fluoro-6-(trifluoromethyl)-; 3-Chloro-2-fluoro-alpha,alpha,α-trifluoro-o-toluoyl chloride
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-2-Fluoro-6-(Trifluoromethyl)Benzoyl Chloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation. Keep away from moisture, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.