Description

2-(1,3-Dimethoxy-1,3-Dioxopropan-2-Yl)-4-Nitrobenzoic Acid is a specialized organic intermediate featuring a nitrobenzoic acid core functionalized with a dimethoxydioxopropan-2-yl group. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a functionalized nitroaromatic scaffold.
• Agrochemical Research: Used in the development of new herbicides, pesticides, and plant growth regulators where its specific substitution pattern can influence biological activity.
• Fine Chemical Synthesis: Acts as a versatile building block for creating complex dyes, pigments, and specialty polymers.
• Academic & Industrial R&D: Employed in medicinal chemistry and material science research for structure-activity relationship (SAR) studies and novel compound library generation.
• Chemical Biology Probes: Potential use in the development of molecular probes and tags due to its reactive nitro and carboxylic acid functional groups.

Basic Information

Product Name	2-(1,3-Dimethoxy-1,3-Dioxopropan-2-Yl)-4-Nitrobenzoic Acid
CAS No.	186390-71-6
Molecular Formula	C₁₃H₁₃NO₈
Molecular Weight	311.25 g/mol
Synonyms	4-Nitro-2-(1,3-dimethoxy-1,3-dioxopropan-2-yl)benzoic acid; 2-(1,3-Dimethoxy-1,3-dioxopropan-2-yl)-4-nitrobenzoic acid; Dimethyl 2-(2-carboxy-5-nitrophenyl)malonate; 2-(2-Carboxy-5-nitrophenyl)malonic acid dimethyl ester; (2-Carboxy-5-nitrophenyl)propanedioic acid dimethyl ester; 186390-71-6; 4-Nitro-α,α-bis(methoxycarbonyl)benzeneacetic acid
EINECS	Contact for details

Quality Control

Our 2-(1,3-Dimethoxy-1,3-Dioxopropan-2-Yl)-4-Nitrobenzoic Acid undergoes rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to verify identity, purity, and consistency across batches. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct or strong artificial light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.