Description

Ethanone, 2-Fluoro-1-[4-(Trifluoromethyl)Phenyl]- (9Ci) is a high-value fluorinated aromatic ketone building block, identified by CAS NO 186297-56-3. This compound is prized for its unique trifluoromethyl and fluoro substituents, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules in advanced synthesis. It is an essential intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials with tailored properties.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for creating molecular probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	Ethanone, 2-Fluoro-1-[4-(Trifluoromethyl)Phenyl]- (9Ci)
CAS No.	186297-56-3
Molecular Formula	C9H6F4O
Molecular Weight	206.14 g/mol
Synonyms	2-Fluoro-1-[4-(trifluoromethyl)phenyl]ethanone; 2-Fluoro-4'-trifluoromethylacetophenone; 1-(4-(Trifluoromethyl)phenyl)-2-fluoroethan-1-one; 4'-(Trifluoromethyl)-2-fluoroacetophenone; α-Fluoro-4-(trifluoromethyl)acetophenone; 2-Fluoro-1-(4-trifluoromethylphenyl)ethanone; FTA; 186297-56-3
EINECS	Contact for details

Quality Control

Our Ethanone, 2-Fluoro-1-[4-(Trifluoromethyl)Phenyl]- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.