Description

3-(1-Tritylimidazol-4-Yl) Propionaldehyde is a specialized, high-value chemical intermediate featuring a trityl-protected imidazole core. This compound is critical for advanced organic synthesis, particularly in the development of novel pharmaceutical compounds and complex bioactive molecules. It is primarily utilized by research institutions and fine chemical manufacturers engaged in medicinal chemistry, process development, and the synthesis of proprietary active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting enzyme inhibition.
• Medicinal Chemistry Research: Used in the discovery and optimization of new chemical entities (NCEs) in academic and industrial R&D labs.
• Process Chemistry: Serves as a critical intermediate in the scale-up and route development for API manufacturing.
• Bioconjugation Chemistry: The aldehyde functional group enables its use in linker chemistry for antibody-drug conjugates (ADCs) or other bioconjugates.
• Ligand Synthesis: Useful for preparing specialized ligands for catalysis or metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of other high-value, low-volume specialty chemicals.

Basic Information

Product Name	3-(1-Tritylimidazol-4-Yl) Propionaldehyde
CAS No.	186096-23-1
Molecular Formula	C25H22N2O
Molecular Weight	366.46 g/mol
Synonyms	3-(1-Triphenylmethyl-1H-imidazol-4-yl)propanal; 4-(3-Oxopropyl)-1-tritylimidazole; 1-Trityl-4-(3-oxopropyl)imidazole; 3-(1-Trityl-1H-imidazol-4-yl)propanal; N-Trityl-4-(3-oxopropyl)imidazole; 3-(1-Tritylimidazol-4-yl)propanal; 1-Tritylimidazole-4-propionaldehyde; 4-(3-Oxopropyl)-1-(triphenylmethyl)-1H-imidazole
EINECS	Contact for details

Quality Control

Our 3-(1-Tritylimidazol-4-Yl) Propionaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for each lot, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.