Description

Cyclohexanecarboxaldehyde, 2-Hydroxy-1-Methyl-, trans- (9Ci) is a specialized chiral aldehyde derivative of cyclohexane, serving as a high-value intermediate in advanced organic synthesis. Its unique stereochemistry and functional groups make it a critical building block for constructing complex molecular architectures with precise spatial orientation. This compound is essential for research and production in the pharmaceutical and fine chemical industries, where it is used to develop active pharmaceutical ingredients (APIs), chiral ligands, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in developing central nervous system (CNS) agents and anti-inflammatory compounds.
• Asymmetric Catalysis: Used in the preparation of chiral ligands and catalysts for enantioselective synthesis, crucial for producing single-isomer compounds.
• Fine Chemical Synthesis: Serves as a precursor for fragrances, flavors, and advanced agrochemicals requiring specific stereochemical properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and material science research.
• Specialty Polymer Modification: Employed to introduce chiral centers or aldehyde functionality into polymer chains for specialized material properties.

Basic Information

Product Name	Cyclohexanecarboxaldehyde, 2-Hydroxy-1-Methyl-, trans- (9Ci)
CAS No.	186038-23-3
Molecular Formula	C8H14O2
Molecular Weight	142.20 g/mol
Synonyms	trans-2-Hydroxy-1-methylcyclohexanecarboxaldehyde; (1R,2S)-2-Hydroxy-1-methylcyclohexanecarbaldehyde; (1S,2R)-2-Hydroxy-1-methylcyclohexanecarbaldehyde; 2-Hydroxy-1-methylcyclohexanecarboxaldehyde, trans-; 1-Methyl-2-hydroxycyclohexanecarbaldehyde; Cyclohexanecarboxaldehyde, 2-hydroxy-1-methyl-, (1R,2S)-rel-; Chiral Cyclohexane Aldehyde Derivative
EINECS	Contact for details

Quality Control

Our production of Cyclohexanecarboxaldehyde, 2-Hydroxy-1-Methyl-, trans- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure consistency and high chemical purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.