Description

2-Bromo-1-(2,5-Difluorophenyl)Propan-1-One is a specialized fluorinated and brominated aromatic ketone, serving as a high-value synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both halogen substituents, makes it a critical building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or insecticides where the difluorophenyl and bromo-ketone groups contribute to biological activity and selectivity.
• Material Science: Building block for synthesizing specialty polymers, liquid crystals, or organic electronic materials that benefit from halogenated aromatic cores.
• Chemical Synthesis: Versatile electrophile in Friedel-Crafts acylation reactions or as a substrate for further functionalization via nucleophilic substitution or cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Academic & R&D: Serves as a valuable reagent in methodological studies and for creating compound libraries in medicinal chemistry and chemical biology research programs.

Basic Information

Product Name	2-Bromo-1-(2,5-Difluorophenyl)Propan-1-One
CAS No.	186036-04-4
Molecular Formula	C9H7BrF2O
Molecular Weight	249.06 g/mol
Synonyms	1-(2,5-Difluorophenyl)-2-bromopropan-1-one; 2-Bromo-1-(2,5-difluorophenyl)-1-propanone; 2-Bromo-1-(2,5-difluorophenyl)propan-1-one; 2-Bromo-1-(2,5-difluorophenyl)acetone; α-Bromo-2',5'-difluoropropiophenone; Propiophenone, 2-bromo-1-(2,5-difluorophenyl)-
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(2,5-Difluorophenyl)Propan-1-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and GC-MS for impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in opaque secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.