Description

3 4 5 6-Tetrafluorofluorescein Diacetate is a key fluorinated derivative of fluorescein, a cornerstone compound in the development of advanced fluorescent probes and sensors. Its value lies in the enhanced photostability and altered spectral properties imparted by the fluorine atoms, making it superior for demanding analytical and diagnostic applications. This high-purity intermediate is essential for researchers and manufacturers in the fields of bioconjugation, cell biology, and diagnostic assay development, where precise labeling and detection are critical.

Application

• Synthesis of Fluorescent Probes and Dyes: Serves as a critical precursor for creating advanced, fluorinated fluorescent labels with improved performance.
• Bioconjugation and Labeling Reagents: Used to develop reactive derivatives (e.g., NHS esters, maleimides) for tagging proteins, antibodies, and nucleic acids.
• Cell Staining and Imaging: A key intermediate for producing cell-permeable fluorescent indicators for live-cell microscopy and flow cytometry.
• Diagnostic Assay Development: Employed in the manufacture of reagents for ELISA, lateral flow assays, and other clinical diagnostic platforms.
• Chemical Sensing: Acts as a building block for constructing molecular sensors that detect specific ions or small molecules based on fluorescence changes.
• Photodynamic Therapy Research: Investigated as a component in the development of photosensitizers due to its derivatizable fluorescein core.

Basic Information

Item	Details
Product Name	3 4 5 6-Tetrafluorofluorescein Diacetate
CAS No.	185318-75-6
Molecular Formula	C24H14F4O7
Molecular Weight	490.36 g/mol
Synonyms	3',6'-Diacetyl-4',5',6,7-tetrafluorofluorescein; Tetrafluorofluorescein Diacetate; 4',5',6,7-Tetrafluorofluorescein Diacetate; 6-Carboxy-3',6'-diacetyl-4',5',6,7-tetrafluorofluorescein; Fluorescein, 4',5',6,7-tetrafluoro-, diacetate; 2-[6-(Acetyloxy)-3-oxo-4,5,6,7-tetrafluoro-3H-xanthen-9-yl]benzoic acid acetate
EINECS	Contact for details

Quality Control

Our 3 4 5 6-Tetrafluorofluorescein Diacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and bioconjugation applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC/IR)	Conforms to standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.