Description

D-Tryptophan, n-[(1,1-Dimethylethoxy)Carbonyl]-2-Methylalanyl-, Methyl Ester is a protected amino acid derivative of significant importance in advanced organic synthesis. This compound serves as a critical building block for the controlled construction of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, bioactive peptides, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for peptide-based therapeutics.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce protected tryptophan and methylalanine residues with high fidelity.
• Bioconjugation & Probe Development: Serves as a precursor for creating fluorescent probes, affinity labels, or other bioconjugates for biochemical research.
• Academic & Industrial R&D: Employed in chemical biology and medicinal chemistry research to study protein-protein interactions and structure-activity relationships (SAR).
• Fine Chemical Production: Acts as a specialized intermediate in the multi-step synthesis of complex, high-value organic molecules.

Basic Information

Product Name	D-Tryptophan, n-[(1,1-Dimethylethoxy)Carbonyl]-2-Methylalanyl-, Methyl Ester
CAS No.	185056-99-9
Molecular Formula	C22H31N3O5
Molecular Weight	417.50 g/mol
Synonyms	Boc-2-MeAla-D-Trp-OMe; Boc-2-Methyl-D-alanyl-D-tryptophan methyl ester; Methyl N-[(2S)-2-[[(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]-3-(1H-indol-3-yl)propanoate]; (R)-2-((S)-2-((tert-Butoxycarbonyl)amino)propanamido)-3-(1H-indol-3-yl)propanoic acid methyl ester; Boc-D-2-MeAla-D-Trp-OMe; N-Boc-2-methyl-D-alanyl-D-tryptophan methyl ester; tert-Butyl ((R)-1-(((S)-1-methoxy-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-1-oxopropan-2-yl)carbamate
EINECS	Contact for details

Quality Control

Our D-Tryptophan, n-[(1,1-Dimethylethoxy)Carbonyl]-2-Methylalanyl-, Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to ensure stereochemical integrity, meeting the stringent requirements of research and pre-clinical development. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under anhydrous conditions when possible to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.