Description

3-(3,5-Bis-Trifluoromethyl-Phenyl)-Propionic Acid Ethyl Ester is a high-value fluorinated aromatic ester, serving as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in the unique reactivity and stability imparted by the bis-trifluoromethylphenyl group, enabling the construction of complex molecules with enhanced properties. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical sectors, where it is used to synthesize novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atoms contribute to improved bioavailability and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of fluorinated polymers and liquid crystals, imparting desirable thermal and chemical resistance.
• Organic Electronics: Investigated as a component in the synthesis of electron-deficient materials for use in organic light-emitting diodes (OLEDs) and semiconductors.
• Custom Synthesis & Scale-Up: A pivotal starting material for contract research organizations (CROs) and custom synthesis manufacturers for client-specific molecule development.

Basic Information

Item	Detail
Product Name	3-(3,5-Bis-Trifluoromethyl-Phenyl)-Propionic Acid Ethyl Ester
CAS No.	184969-50-4
Molecular Formula	C14H12F6O2
Molecular Weight	326.24 g/mol
Synonyms	Ethyl 3-[3,5-bis(trifluoromethyl)phenyl]propanoate; 3-[3,5-Bis(trifluoromethyl)phenyl]propionic Acid Ethyl Ester; 3,5-Bis(trifluoromethyl)benzenepropanoic Acid Ethyl Ester; Ethyl 3-(3,5-Bis(trifluoromethyl)phenyl)propionate; 184969-50-4; 3-(3,5-Bis(trifluoromethyl)phenyl)propanoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of 3-(3,5-Bis-Trifluoromethyl-Phenyl)-Propionic Acid Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider using inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.