Description

3,5-Bis(Trifluoro-Methyl)Cinnamic Ethyl Ester is a high-value fluorinated organic intermediate characterized by its cinnamate ester backbone and two electron-withdrawing trifluoromethyl groups. This molecular architecture is critical for imparting enhanced metabolic stability, lipophilicity, and unique electronic properties to final compounds. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of advanced active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of potential drug candidates, particularly in areas like oncology, CNS disorders, and anti-inflammatory agents, where the trifluoromethyl groups can improve bioavailability and binding affinity.
• Agrochemical Synthesis: Used in developing advanced herbicides, fungicides, and insecticides, where its structure contributes to the efficacy and environmental profile of the final product.
• Material Science Research: Serves as a precursor for specialty monomers or ligands in the development of advanced polymers, coatings, or metal-organic frameworks (MOFs) with specific fluorinated properties.
• Liquid Crystal & OLED Materials: Investigated as a component in the synthesis of fluorinated liquid crystals or organic light-emitting diode (OLED) materials due to its potential influence on electronic properties and stability.
• Chemical Biology Probes: Utilized in the design and creation of molecular probes and tags for studying biological processes, leveraging the distinctive properties of the fluorine atoms.

Basic Information

Product Name	3,5-Bis(Trifluoro-Methyl)Cinnamic Ethyl Ester
CAS No.	184969-49-1
Molecular Formula	C14H10F6O2
Molecular Weight	324.22 g/mol
Synonyms	Ethyl 3,5-Bis(trifluoromethyl)cinnamate; Ethyl (E)-3-[3,5-Bis(trifluoromethyl)phenyl]acrylate; Ethyl (E)-3-[3,5-Bis(trifluoromethyl)phenyl]-2-propenoate; 3,5-Bis(trifluoromethyl)cinnamic acid ethyl ester; (E)-Ethyl 3-(3,5-bis(trifluoromethyl)phenyl)acrylate; 2-Propenoic acid, 3-[3,5-bis(trifluoromethyl)phenyl]-, ethyl ester, (E)-
EINECS	Contact for details

Quality Control

Our 3,5-Bis(Trifluoro-Methyl)Cinnamic Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.