Description

Methyl 3,3,3-Trifluoro-2-Phenylpropionate CAS NO 184414-29-7 is a high-value fluorinated organic ester building block. This compound is essential for introducing the trifluoromethylphenyl moiety, a key structural feature that enhances the metabolic stability and lipophilicity of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the trifluoromethyl group improves biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystals used in high-performance displays due to its influence on dielectric anisotropy and viscosity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, such as Suzuki-Miyaura couplings, and ester hydrolysis/transformation reactions to create diverse fluorinated compounds.
• Material Science Research: Investigated for the development of specialty polymers and coatings with unique surface properties and chemical resistance.

Basic Information

Product Name	Methyl 3,3,3-Trifluoro-2-Phenylpropionate
CAS No.	184414-29-7
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	Methyl 2-Phenyl-3,3,3-trifluoropropionate; 3,3,3-Trifluoro-2-phenylpropionic Acid Methyl Ester; Methyl α-Phenyl-β,β,β-trifluoropropionate; Methyl (3,3,3-Trifluoro-2-phenyl)propanoate; Methyl 3,3,3-Trifluoro-2-phenylpropanoate; 2-Phenyl-3,3,3-trifluoropropionic Acid Methyl Ester; MFCD03094066; (RS)-Methyl 3,3,3-trifluoro-2-phenylpropionate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed to confirm identity, purity, and impurity profile. Certificates of Analysis (COA) detailing specific results for purity (typically by GC or HPLC), residual solvents, and other critical parameters are available upon request. We adhere to a cGMP-compliant quality management system to ensure batch-to-batch consistency for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.