Description

4-(Trifluoromethoxy)Cinnamic Aldehyde is a high-purity fluorinated aromatic aldehyde building block, essential for advanced organic synthesis. Its unique trifluoromethoxy substituent imparts significant lipophilicity and metabolic stability, making it a valuable intermediate for creating novel compounds with enhanced properties. This chemical is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethoxy group can improve biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved dielectric anisotropy and stability.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, condensations, and as a precursor for corresponding acids and alcohols in custom synthesis projects.
• Flavor & Fragrance Research: Investigated for creating novel aromatic compounds with unique olfactory profiles due to its cinnamic aldehyde backbone.

Basic Information

Product Name	4-(Trifluoromethoxy)Cinnamic Aldehyde
CAS No.	183800-94-4
Molecular Formula	C₁₀H₇F₃O₂
Molecular Weight	216.16 g/mol
Synonyms	3-[4-(Trifluoromethoxy)phenyl]prop-2-enal; 4-(Trifluoromethoxy)benzylideneacetaldehyde; p-(Trifluoromethoxy)cinnamaldehyde; (E)-3-[4-(Trifluoromethoxy)phenyl]acrylaldehyde; 4-Trifluoromethoxycinnamaldehyde; 4-(Trifluoromethoxy)cinnaldehyde; (E)-4-(Trifluoromethoxy)cinnamaldehyde
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethoxy)Cinnamic Aldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.