Description

4-Bromobenzeneboronic Acid Neopentyl Glycol Ester is a protected boronic acid derivative, a crucial intermediate in modern synthetic organic chemistry. Its primary value lies in its enhanced stability compared to the free boronic acid, making it a reliable and versatile reagent for Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific biphenyl or heterobiaryl structures.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Biology Probes: Utilized in the development of molecular probes and bioconjugates for diagnostic and research applications.
• Custom Synthesis & Scale-up: A reliable starting material for contract research and manufacturing organizations (CROs/CMOs) performing custom synthesis projects.

Basic Information

Product Name	4-Bromobenzeneboronic Acid Neopentyl Glycol Ester
CAS No.	183677-71-6
Molecular Formula	C13H18BBrO2
Molecular Weight	297.00 g/mol
Synonyms	4-Bromophenylboronic Acid Neopentyl Glycol Ester; (4-Bromophenyl)boronic Acid Neopentyl Ester; 2-(4-Bromophenyl)-5,5-dimethyl-1,3,2-dioxaborinane; 4-Bromobenzeneboronic Acid Pinned Ester; B-(4-Bromophenyl)-5,5-dimethyl-1,3,2-dioxaborinane; 4-Bromobenzene-1-boronic Acid Neopentyl Glycol Cyclic Ester; Neopentyl Glycol (4-Bromophenyl)boronate
EINECS	Contact for details

Quality Control

Our 4-Bromobenzeneboronic Acid Neopentyl Glycol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening the container to prevent hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.