Description

Oxiranecarboxylic Acid, 3-(Chlorocarbonyl)-, Ethyl Ester, (2S-Trans)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant value in advanced organic synthesis. Its core value proposition lies in its bifunctional epoxide and activated ester moieties, enabling precise and efficient construction of complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals requiring specific stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of chiral pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Modification: Can be utilized to introduce reactive epoxide and ester functionalities into polymer chains for specialty materials.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and labeled compounds for biochemical research.
• Fine Chemical Production: A versatile intermediate for the multi-step synthesis of complex natural products and specialty chemicals.

Basic Information

Product Name	Oxiranecarboxylic Acid, 3-(Chlorocarbonyl)-, Ethyl Ester, (2S-Trans)- (9Ci)
CAS No.	183508-40-9
Molecular Formula	C6H7ClO4
Molecular Weight	178.57 g/mol
Synonyms	(2S,3S)-3-(Chlorocarbonyl)oxirane-2-carboxylic acid ethyl ester; Ethyl (2S,3S)-3-(chlorocarbonyl)oxirane-2-carboxylate; (-)-Ethyl (2S,3S)-3-(chlorocarbonyl)oxirane-2-carboxylate; trans-Ethyl 3-(chloroformyl)oxirane-2-carboxylate; (2S,3S)-Epoxysuccinic acid ethyl ester chloroformate; Chiral epoxysuccinate derivative; (2S,3S)-Ethyl oxiranedicarboxylate chloroformate
EINECS	Contact for details

Quality Control

Our production of Oxiranecarboxylic Acid, 3-(Chlorocarbonyl)-, Ethyl Ester, (2S-Trans)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and GC-MS to confirm identity, enantiomeric excess, and impurity profile. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.