Description

Ethanone, 1-(4,5-Difluoro-2-Methylphenyl)- (9Ci) is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its value lies in its precise molecular structure, which serves as a critical intermediate for constructing more complex molecules in regulated industries. This compound is primarily needed by research and development teams, process chemists, and manufacturers within the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of new drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the difluoro and methyl substituents can contribute to specific biological activity and environmental persistence profiles.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, or organic electronic materials that benefit from fluorinated aromatic units.
• Chemical Reference Standard: Employed in analytical laboratories for method development, calibration, and quality control testing of related substances.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	Ethanone, 1-(4,5-Difluoro-2-Methylphenyl)- (9Ci)
CAS No.	183237-85-6
Molecular Formula	C9H8F2O
Molecular Weight	170.16 g/mol
Synonyms	1-(4,5-Difluoro-2-methylphenyl)ethanone; 4',5'-Difluoro-2'-methylacetophenone; 2-Methyl-4,5-difluoroacetophenone; 4,5-Difluoro-2-methylacetophenone; 1-Acetyl-4,5-difluoro-2-methylbenzene; 4,5-Difluoro-2-methylphenyl methyl ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(4,5-Difluoro-2-Methylphenyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.