Description

3,4-Dibenzofurandiol, 3,4-Dihydro-, (3S-Cis)- (9Ci) is a chiral, dihydroxylated dibenzofuran derivative with the CAS number 183180-96-3. This compound serves as a valuable chiral building block and synthetic intermediate in advanced organic synthesis, particularly for the development of complex molecules with specific stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, asymmetric synthesis, and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including potential central nervous system (CNS) drugs and enzyme inhibitors.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in catalytic asymmetric reactions to construct complex, enantiomerically pure molecular architectures.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes due to its fused aromatic and diol functionality.
• Ligand and Catalyst Development: Serves as a precursor for the synthesis of chiral ligands used in transition metal catalysis.
• Advanced Material Research: Investigated as a monomer or core structure for the synthesis of specialty polymers and functional organic materials.
• Academic and Industrial R&D: Used in chemical research laboratories for methodological development and exploring new synthetic pathways.

Basic Information

Product Name	3,4-Dibenzofurandiol, 3,4-Dihydro-, (3S-Cis)- (9Ci)
CAS No.	183180-96-3
Molecular Formula	C₁₂H₁₀O₃
Molecular Weight	202.21 g/mol
Synonyms	(3S,4S)-3,4-Dihydro-3,4-dibenzofurandiol; (3S-cis)-3,4-Dihydro-3,4-dibenzofurandiol; 3,4-Dihydro-3,4-dihydroxydibenzofuran (cis-); cis-3,4-Dihydro-3,4-dibenzofurandiol; 3,4-Dihydroxy-3,4-dihydrodibenzofuran; 3,4-Dihydrodibenzofuran-3,4-diol; (3S,4S)-3,4-Dihydroxy-3,4-dihydrodibenzofuran
EINECS	Contact for details

Quality Control

Our 3,4-Dibenzofurandiol, 3,4-Dihydro-, (3S-Cis)- (9Ci) is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and key analytical data. We support custom synthesis and can tailor specifications, including purity grade and packaging, to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.