Description

tert-Butyl 2-(3-Aminophenyl)Acetate is a high-purity aromatic amine derivative, serving as a critical protected intermediate in advanced organic synthesis. Its primary value lies in providing a versatile building block for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Monomer or modifier for creating specialty polymers with specific functional properties.
• Dye and Pigment Intermediate: Serves in the synthesis of complex organic colorants and imaging agents.
• Academic and Contract Research: Essential reagent for methodological development and scale-up studies in academic and industrial R&D laboratories.

Basic Information

Product Name	tert-Butyl 2-(3-Aminophenyl)Acetate
CAS No.	183180-53-2
Molecular Formula	C12H17NO2
Molecular Weight	207.27 g/mol
Synonyms	3-Aminobenzeneacetic acid 1,1-dimethylethyl ester; 2-(3-Aminophenyl)acetic acid tert-butyl ester; tert-Butyl (3-aminophenyl)acetate; 3-(tert-Butoxycarbonylmethyl)aniline; Benzenacetic acid, 3-amino-, 1,1-dimethylethyl ester; 183180-53-2; tert-Butyl 3-aminobenzeneacetate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(3-Aminophenyl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical characteristics are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its sensitivity to oxidation and light, prolonged exposure to air or direct light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.