Description

3-(tert-Butylaminocarbonyl)Phenylboronic Acid is a specialized organoboron compound that serves as a valuable synthetic intermediate. Its core value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a protected amine moiety, enabling precise molecular construction. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex, nitrogen-containing target molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates containing biaryl and aniline motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-amine architectures.
• Material Science Research: Employed in the creation of organic electronic materials, such as those for OLEDs or conductive polymers, where the boronic acid group facilitates polymerization or functionalization.
• Ligand and Catalyst Development: Serves as a precursor for creating novel bidentate ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-(tert-Butylaminocarbonyl)Phenylboronic Acid
CAS No.	183158-30-7
Molecular Formula	C11H16BNO3
Molecular Weight	221.06 g/mol
Synonyms	[3-[(1,1-Dimethylethyl)aminocarbonyl]phenyl]boronic Acid; 3-(tert-Butylcarbamoyl)benzeneboronic Acid; 3-(Boc-amino)phenylboronic Acid (common misnomer); 3-Carbamoylphenylboronic Acid tert-butyl derivative; 3-(N-tert-Butylaminocarbonyl)phenylboronic Acid; B-[3-[[(1,1-Dimethylethyl)amino]carbonyl]phenyl]-boronic Acid
EINECS	Contact for details

Quality Control

Our 3-(tert-Butylaminocarbonyl)Phenylboronic Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.