Description

7-Fluoro-6-Methyl-3,4-Dihydro-2H-Naphthalen-1-One is a high-purity fluorinated ketone building block of significant interest in advanced organic synthesis. This compound matters as a critical intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine and specific ring systems into target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for novel organic electronic materials and liquid crystals.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in fluorination and ring-forming reactions.
• Custom Synthesis Building Block: Provides a versatile scaffold for medicinal chemistry and the preparation of compound libraries for high-throughput screening.

Basic Information

Product Name	7-Fluoro-6-Methyl-3,4-Dihydro-2H-Naphthalen-1-One
CAS No.	182182-24-7
Molecular Formula	C₁₁H₁₁FO
Molecular Weight	178.20 g/mol
Synonyms	7-Fluoro-6-methyl-3,4-dihydronaphthalen-1(2H)-one; 1(2H)-Naphthalenone, 7-fluoro-3,4-dihydro-6-methyl-; 7-Fluoro-6-methyl-1-tetralone; 6-Methyl-7-fluoro-1-tetralone; 7-Fluoro-6-methyl-α-tetralone; Fluorinated Tetralone Derivative; FMT Intermediate
EINECS	Contact for details

Quality Control

Every batch of 7-Fluoro-6-Methyl-3,4-Dihydro-2H-Naphthalen-1-One is manufactured under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, GC, NMR, and MS analysis, to ensure compliance with exacting customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.