Description

tert-Butyl 1-Formyl-7-Azabicyclo[2.2.1]Heptane-7-Carboxylate is a high-value, advanced pharmaceutical intermediate featuring a unique bridged bicyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of new therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel drugs, including those targeting neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex Active Pharmaceutical Ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used in the design and development of new drug candidates, especially those requiring a constrained, nitrogen-containing bicyclic scaffold.
• Process Chemistry Development: Serves as a critical starting material or intermediate in the scale-up and optimization of synthetic routes for target molecules.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying biological pathways and target engagement.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	tert-Butyl 1-Formyl-7-Azabicyclo[2.2.1]Heptane-7-Carboxylate
CAS No.	182137-54-8
Molecular Formula	C12H19NO3
Molecular Weight	225.28 g/mol
Synonyms	7-tert-Butoxycarbonyl-7-azabicyclo[2.2.1]heptane-1-carboxaldehyde; 1-Formyl-7-azabicyclo[2.2.1]heptane-7-carboxylic acid tert-butyl ester; 7-Boc-7-azabicyclo[2.2.1]heptane-1-carbaldehyde; 7-Azabicyclo[2.2.1]heptane-1-carboxaldehyde, 7-(1,1-dimethylethyl) ester; tert-Butyl 1-formyl-7-aza-2-azoniabicyclo[2.2.1]heptane-7-carboxylate; 7-N-Boc-7-azabicyclo[2.2.1]heptane-1-carboxaldehyde; 1-Formyl-7-azabicyclo[2.2.1]heptane-7-carboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-Formyl-7-Azabicyclo[2.2.1]Heptane-7-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, meeting the rigorous demands of pharmaceutical R&D. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques. We adhere to industry best practices and can support development projects requiring material manufactured under GMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is easily oxidized and moisture-sensitive; prolonged exposure to air should be avoided.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.