Description

4-Chloro-2-Iodo-Benzoic Acid Methyl Ester is a halogenated aromatic ester building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for constructing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a precursor for liquid crystals, organic semiconductors, and other functional materials.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Stille couplings.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Chloro-2-Iodo-Benzoic Acid Methyl Ester
CAS No.	181765-85-5
Molecular Formula	C8H6ClIO2
Molecular Weight	296.49 g/mol
Synonyms	Methyl 4-Chloro-2-iodobenzoate; Benzoic acid, 4-chloro-2-iodo-, methyl ester; 4-Chloro-2-iodobenzoic acid methyl ester; Methyl 4-chloro-2-iodobenzoate; 2-Iodo-4-chlorobenzoic acid methyl ester; 181765-85-5; Methyl 2-iodo-4-chlorobenzoate
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Iodo-Benzoic Acid Methyl Ester is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. The product is light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.