Description

3',5'-Difluoro-2-Phenylacetophenone is a high-purity fluorinated aromatic ketone building block. This compound is valued for its role as a key intermediate in the synthesis of complex organic molecules, particularly in advanced pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing difluorophenyl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides where the fluorinated aromatic structure imparts desired biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and liquid crystals.
• Fluorine Chemistry Studies: Acts as a model substrate for studying the reactivity and incorporation of fluorine atoms in complex molecular architectures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	3',5'-Difluoro-2-Phenylacetophenone
CAS No.	181697-20-1
Molecular Formula	C14H10F2O
Molecular Weight	232.23 g/mol
Synonyms	1-(3,5-Difluorophenyl)-2-phenylethan-1-one; 2-Phenyl-1-(3,5-difluorophenyl)ethanone; 3,5-Difluorobenzyl Phenyl Ketone; (3,5-Difluorophenyl)(phenyl)methanone, Ethanone Derivative; DFPE
EINECS	Contact for details

Quality Control

Our 3',5'-Difluoro-2-Phenylacetophenone is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.