Description

4-Pyridineboronic Acid Pinacol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient and selective carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require the precise construction of complex pyridine-containing molecules.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing functionalized pyridine cores for kinase inhibitors and other therapeutics.
• Agrochemical Synthesis: Used to create novel pyridine-based herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand & Catalyst Development: Serves as a precursor for constructing sophisticated nitrogen-containing ligands used in homogeneous catalysis.
• Materials Science: Building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers, where the pyridine moiety modifies electronic properties.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and bioconjugates for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A high-value starting material for custom synthesis projects requiring the introduction of a pyridyl group under mild, palladium-catalyzed conditions.

Basic Information

Item	Details
Product Name	4-Pyridineboronic Acid Pinacol Ester
CAS No.	181219-01-2
Molecular Formula	C11H16BNO2
Molecular Weight	205.06 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-Pyridinylboronic Acid Pinacol Ester; 2-(Pyridin-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Pyridylboronic Acid Pinacol Ester; Pinacol 4-Pyridylboronate; 4-Pyridineboronic Acid Neopentyl Glycol Ester (common alternative); 4-Pyridyl-BPin
EINECS	Contact for details

Quality Control

Our 4-Pyridineboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.