Description

Ethanone, 2,2,2-Trifluoro-1-(3-Phenyloxiranyl)- (9Ci) is a specialized trifluoromethyl ketone derivative featuring a phenyloxirane (styrene oxide) moiety, making it a valuable chiral synthon and building block in advanced organic synthesis. This compound matters for its role in introducing the trifluoroacetyl group and epoxide functionality, which are critical for modulating the physicochemical and biological properties of target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Asymmetric Catalysis: Acts as a substrate or ligand precursor in catalytic reactions to create enantiomerically pure compounds.
• Material Science Research: Employed in the development of specialty polymers and advanced materials with unique surface properties.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research exploring new methodologies for C-F bond formation and functionalization.
• Ligand and Catalyst Development: Utilized in the design and synthesis of novel chiral ligands for transition metal catalysis.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-(3-Phenyloxiranyl)- (9Ci)
CAS No.	180743-44-6
Molecular Formula	C10H7F3O2
Molecular Weight	216.16 g/mol
Synonyms	2,2,2-Trifluoro-1-(3-phenyloxiranyl)ethanone; 1-(3-Phenyloxiran-2-yl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(oxiran-2-ylphenyl)ethanone; (3-Phenyloxiran-2-yl)(trifluoro)methanone; Trifluoro(3-phenyloxiran-2-yl)methanone; α,α,α-Trifluoro-3-phenyloxiran-2-yl methyl ketone; Styrene oxide trifluoroacetate derivative
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-(3-Phenyloxiranyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as assay, enantiomeric excess (if applicable), and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white solid or clear colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.