Description

3-(4-Trifluoromethyl-Phenyl)-Propan-1-Ol is a versatile fluorinated aromatic alcohol intermediate. This compound is valued for its trifluoromethylphenyl group, which imparts unique electronic and steric properties critical for modifying the biological activity and physicochemical characteristics of target molecules. It is primarily sought by R&D and production teams in the pharmaceutical and agrochemical sectors for the synthesis of advanced active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for display technologies.
• Organic Synthesis: A valuable reagent for introducing the 4-(trifluoromethyl)benzyl alcohol moiety into more complex molecular architectures.
• Polymer Modification: Employed to create specialty monomers for polymers with enhanced chemical resistance and specific optical properties.
• Chemical Research: Used in academic and industrial R&D for exploring structure-activity relationships (SAR) in medicinal chemistry.

Basic Information

Product Name	3-(4-Trifluoromethyl-Phenyl)-Propan-1-Ol
CAS No.	180635-74-9
Molecular Formula	C10H11F3O
Molecular Weight	204.19 g/mol
Synonyms	3-[4-(Trifluoromethyl)phenyl]propan-1-ol; 4-(3-Hydroxypropyl)benzotrifluoride; 3-(4-Trifluoromethylphenyl)-1-propanol; 1-Propanol, 3-[4-(trifluoromethyl)phenyl]-; α,α,α-Trifluoro-4-(3-hydroxypropyl)toluene; 4-(Trifluoromethyl)phenylpropanol; 3-(p-Trifluoromethylphenyl)propanol; 4-(3-Hydroxypropyl)-α,α,α-trifluorotoluene
EINECS	Contact for details

Quality Control

Our 3-(4-Trifluoromethyl-Phenyl)-Propan-1-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for all commercial shipments. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.