Description

4-Carboxylphenylboronic Acid Pinacol Ester is a protected boronic acid derivative, a crucial intermediate in modern synthetic organic chemistry. Its value lies in its dual functionality, offering a protected boronic acid handle for Suzuki-Miyaura cross-coupling reactions while presenting a carboxylic acid group for further derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing complex biaryl structures and advanced molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via Suzuki-Miyaura cross-coupling.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides requiring specific biaryl motifs.
• Material Science Research: Serves as a monomer or precursor for creating functional organic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for biological target identification and study.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and fine chemical suppliers performing bespoke synthesis.

Basic Information

Product Name	4-Carboxylphenylboronic Acid Pinacol Ester
CAS No.	180516-87-4
Molecular Formula	C14H19BO4
Molecular Weight	262.11 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic Acid; Benzoic acid, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 4-Bpin Benzoic Acid; 4-Carboxyphenylboronic Acid Pinacol Ester; 4-(Pinacolatoboryl)benzoic Acid; 4-Boronobenzoic Acid Pinacol Ester; p-Carboxyphenylboronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our 4-Carboxylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.