Description

Ethanone, 2,2,2-Trifluoro-1-(2-Methoxy-5-Methylphenyl)- (9Ci) is a specialized trifluoromethyl ketone derivative, a key fluorinated building block valued for its unique electronic and steric properties. This compound is critical for introducing the trifluoroacetyl group into complex molecular architectures, enabling the development of advanced materials and active pharmaceutical ingredients. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in medicinal chemistry, catalysis, and specialty polymer synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis, improving enantioselectivity in critical bond-forming reactions.
• Advanced Material Precursor: Employed in the synthesis of fluorinated polymers and liquid crystals, contributing to improved thermal stability, chemical resistance, and optical properties.
• Chemical Research & Development: A versatile reagent for exploring new fluorination methodologies and constructing complex heterocyclic compounds in academic and industrial R&D settings.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-(2-Methoxy-5-Methylphenyl)- (9Ci)
CAS No.	180311-39-1
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	1-(2-Methoxy-5-methylphenyl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(2-methoxy-5-methylphenyl)ethanone; 2-Methoxy-5-methyl-α,α,α-trifluoroacetophenone; 2'-Methoxy-5'-methyl-2,2,2-trifluoroacetophenone; α,α,α-Trifluoro-2-methoxy-5-methylacetophenone; 5-Methyl-2-methoxyphenyl trifluoromethyl ketone; TFMMAP (abbreviation)
EINECS	Contact for details

Quality Control

Our production of Ethanone, 2,2,2-Trifluoro-1-(2-Methoxy-5-Methylphenyl)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.