Description

3,3-Dimethyl-4'-Fluorobutyrophenone is a high-purity fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. Its unique structure, featuring a fluorinated aromatic ring and a hindered ketone side chain, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated components for electronic display materials and organic light-emitting diodes.
• Advanced Polymer Chemistry: Employed as a monomer or cross-linking agent for creating specialty polymers with specific thermal and optical properties.
• Chemical Research & Development: A versatile building block in medicinal chemistry and material science for structure-activity relationship (SAR) studies and novel compound libraries.
• Flavor & Fragrance Ingredient Synthesis: Used in the multi-step synthesis of complex aromatic molecules for high-value fragrance applications.

Basic Information

Product Name	3,3-Dimethyl-4'-Fluorobutyrophenone
CAS No.	180305-22-0
Molecular Formula	C12H15FO
Molecular Weight	194.25 g/mol
Synonyms	4'-Fluoro-3,3-dimethylbutyrophenone; 1-(4-Fluorophenyl)-3,3-dimethylbutan-1-one; 3,3-Dimethyl-1-(4-fluorophenyl)butan-1-one; p-Fluoro-3,3-dimethylbutyrophenone; Butan-1-one, 1-(4-fluorophenyl)-3,3-dimethyl-; 180305-22-0; FC-6587 (Potential research code)
EINECS	Contact for details

Quality Control

Our 3,3-Dimethyl-4'-Fluorobutyrophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.