Description

2H-Cyclopenta[B]Pyridin-2-One,Octahydro-4-Methyl-,(4-α-,4A-Bta-,7A-Bta-)-(9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex, stereochemically defined bicyclic structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), where its precise stereochemistry is essential for biological activity and process consistency. It is primarily needed by R&D chemists and process development teams in the pharmaceutical and biotechnology industries for creating new therapeutic agents, particularly in central nervous system (CNS) and antiviral research.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of proprietary drug candidates and novel chemical entities.
• CNS Drug Research: Serves as a core scaffold for developing compounds targeting neurological receptors and pathways.
• Antiviral Agent Development: Used in the research and process development of potential antiviral medications.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale manufacturing for clinical trial material.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in stereoselective catalytic reactions.
• Academic & Contract Research: Supplied to universities and CROs for medicinal chemistry programs and structure-activity relationship (SAR) studies.

Basic Information

Product Name	2H-Cyclopenta[B]Pyridin-2-One,Octahydro-4-Methyl-,(4-α-,4A-Bta-,7A-Bta-)-(9Ci)
CAS No.	179685-94-0
Molecular Formula	C9H15NO
Molecular Weight	153.22 g/mol
Synonyms	Octahydro-4-methyl-2H-cyclopenta[b]pyridin-2-one; (4α,4aβ,7aβ)-Octahydro-4-methyl-2H-cyclopenta[b]pyridin-2-one; 4-Methyloctahydro-2H-cyclopenta[b]pyridin-2-one; 179685-94-0; 2H-Cyclopenta[b]pyridin-2-one, octahydro-4-methyl-, (4α,4aβ,7aβ)-; cis-4-Methyloctahydro-2H-cyclopenta[b]pyridin-2-one; Bicyclic lactam intermediate
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality management systems and undergoes comprehensive analytical characterization to ensure identity, purity, and stereochemical integrity. Standard testing includes chiral HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support development and commercial projects requiring cGMP standards and full regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.