Description

Macrocarpal J is a specialized diterpene dialdehyde compound derived from *Eucalyptus* species, recognized for its unique biological activity profile. This high-purity compound is valued for its role as a key intermediate and reference standard in advanced research and development. It is primarily utilized by the pharmaceutical, biotechnology, and natural product chemistry sectors for applications in antimicrobial studies, enzyme inhibition assays, and the synthesis of novel bioactive derivatives.

Application

• Pharmaceutical Research: Serves as a reference standard and active pharmaceutical ingredient (API) intermediate in the development of new antimicrobial and anti-inflammatory agents.
• Biochemical Studies: Used as a potent inhibitor in enzyme interaction studies, particularly targeting bacterial enzymes like DNA gyrase and topoisomerase IV.
• Natural Product Chemistry: Acts as a crucial building block for the semi-synthesis of novel diterpenoid analogs with enhanced or modified biological properties.
• Cosmeceutical Development: Investigated for potential application in topical formulations targeting skin microbiota due to its antimicrobial properties.
• Academic Research: Employed in university and institutional labs for structure-activity relationship (SAR) studies and mechanistic investigations.
• Quality Control: Functions as an analytical standard for the identification and quantification of Macrocarpal J in complex botanical extracts and finished products.

Basic Information

Item	Details
Product Name	Macrocarpal J
CAS No.	179603-47-5
Molecular Formula	C₂₅H₃₄O₅
Molecular Weight	414.53 g/mol
Synonyms	Macrocarpal J; (1R,2S,5S,7S,10R,11S,14S)-5,14-Dihydroxy-2,6,6,11,15,15-hexamethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-5,14-dicarbaldehyde; Eucalyptus Diterpene Dialdehyde; 5,14-Dihydroxy-2,6,6,11,15,15-hexamethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-5,14-dicarboxaldehyde
EINECS	Contact for details

Quality Control

Our Macrocarpal J is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom purity grades, including >95%, >98%, and >99%, are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and ensure long-term stability. The container should be kept in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.