Description

Ethyl 2-(Trifluoromethyl Sulfonyloxy) Benzoate is a high-value, specialized organic intermediate featuring a reactive sulfonyloxy ester group. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique trifluoromethyl and benzoate functionalities enable precise structural modifications. It serves as a key building block for researchers and process chemists developing active pharmaceutical ingredients (APIs), advanced crop protection agents, and novel materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those requiring trifluoromethylated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group often contributes to improved efficacy and environmental profile.
• Material Science Research: Serves as a monomer or modifying agent in the creation of specialty polymers and advanced organic materials with specific electronic or surface properties.
• Chemical Synthesis: Acts as an electrophilic reagent or protecting group in complex organic transformations, including cross-coupling reactions and nucleophilic substitutions.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel ligands and organocatalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	Ethyl 2-(Trifluoromethyl Sulfonyloxy) Benzoate
CAS No.	179538-97-7
Molecular Formula	C10H9F3O5S
Molecular Weight	298.24 g/mol
Synonyms	Ethyl 2-[(Trifluoromethyl)sulfonyl]oxybenzoate; Benzoic acid, 2-[(trifluoromethyl)sulfonyl]oxy-, ethyl ester; 2-(Trifluoromethanesulfonyloxy)benzoic acid ethyl ester; Ethyl O-triflylsalicylate; Ethyl 2-(triflyloxy)benzoate; TFSO-Bz-OEt
EINECS	Contact for details

Quality Control

Our Ethyl 2-(Trifluoromethyl Sulfonyloxy) Benzoate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.