Description

3-(3-Trifluoromethoxy-Phenyl)-Propionic Acid Ethyl Ester is a high-value fluorinated aromatic ester building block, prized for its unique trifluoromethoxy substituent which imparts enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for research and development in advanced organic synthesis, particularly for creating novel chemical entities. It is primarily sought by pharmaceutical, agrochemical, and advanced material scientists for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and reductions to introduce the 3-(trifluoromethoxy)phenyl moiety into more complex molecular architectures.
• Chemical Research & Development: Used in academic and industrial R&D labs for method development and exploring structure-activity relationships (SAR).

Basic Information

Product Name	3-(3-Trifluoromethoxy-Phenyl)-Propionic Acid Ethyl Ester
CAS No.	179381-93-2
Molecular Formula	C12H13F3O3
Molecular Weight	262.23 g/mol
Synonyms	Ethyl 3-[3-(Trifluoromethoxy)phenyl]propanoate; 3-(3-Trifluoromethoxyphenyl)propionic Acid Ethyl Ester; Ethyl 3-(3-Trifluoromethoxyphenyl)propionate; 3-(3-(Trifluoromethoxy)phenyl)propanoic Acid Ethyl Ester; 179381-93-2; 3-(3-Trifluoromethoxy-phenyl)-propionic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 3-(3-Trifluoromethoxy-Phenyl)-Propionic Acid Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We employ advanced analytical techniques including GC, HPLC, NMR, and MS for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.