Description

4,6-Methano-1,3,2-Benzodioxaborole-2-Methanamine is a specialized organoboron compound featuring a fused bicyclic structure. This chemical is valued for its role as a key synthetic intermediate and ligand in advanced organic transformations, particularly in cross-coupling reactions and catalysis. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of complex drug candidates, especially those containing boron for Boron Neutron Capture Therapy (BNCT) or as enzyme inhibitors.
• Catalysis & Ligand Chemistry: Acts as a precursor for generating novel ligands used in transition metal catalysis for C-C and C-X bond formation.
• Agrochemical Research: Employed in the development of new pesticides and herbicides, leveraging its unique heterocyclic structure for bioactivity.
• Materials Science: Used in the research and development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient boron-containing core.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Item	Detail
Product Name	4,6-Methano-1,3,2-Benzodioxaborole-2-Methanamine
CAS No.	179324-86-8
Molecular Formula	C9H10BNO2
Molecular Weight	174.99 g/mol
Synonyms	2-(Aminomethyl)-4,6-methano-1,3,2-benzodioxaborole; 2-Aminomethyl-4,6-methano-1,3,2-benzodioxaborole; 4,6-Methano-1,3,2-benzodioxaborol-2-methanamine; 1,3,2-Benzodioxaborole-2-methanamine, 4,6-methano-; Bicyclic boronate ester amine; 2-(Aminomethyl)benzo[d][1,3,2]dioxaborole-4,6-diyl)dimethane
EINECS	Contact for details

Quality Control

Our 4,6-Methano-1,3,2-Benzodioxaborole-2-Methanamine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR), to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.